Is Cymbalta a good cure for depression?

 Cymbalta (an SSNRI) targets two chemicals, serotonin and norepinephrine, that are believed to play a role in how the brain and body affect mood and pain.

My friend is on the medicine and she doesn't like it at all.

This is about the drug: The Science Behind Cymbalta

Depression may be caused by an imbalance of naturally-occurring chemicals, serotonin and norepinephrine, in the brain and the body. In the brain, these two chemicals are thought to be associated with mood. These same chemicals are thought to be associated with regulating and reducing feelings of pain that come from the body. 


If these chemicals are out of balance, the effect can be felt in both the brain and body. You can feel both the emotional and painful physical symptoms of depression.


Many antidepressants target one chemical, serotonin. Cymbalta also targets a second chemical, norepinephrine. In clinical trials, Cymbalta was proven effective in treating depression, both its emotional and physical symptoms.


Cymbalta is not a narcotic. 


My friend says the it makes her nausiated and she has been sick a few times. She was going to give it another week and then maybe try something different.


Bi-Polar disorder, also known as Manic Depressive is a series of highs and lows. Where depression is all lows. Does that make sense? Here are some red flags for Mania.

Increased Energy

Decreased Sleep


Little Fatigue


An Increase in Activities


Restlessness 

Speech Disruptions

Rapid, Pressured Speech


Incoherent Speech (generally not present in hypomania)


Clang Associations: the association of words based on their sound

(For example, my ex-husband once carried on for some time about vacancies, vagrancies and bacon seeds.) 

Impaired Judgment

Lack of Insight


Inappropriate Humor


Inappropriate Behaviors


Impulsive Behaviors


Financial Extravagance


Grandiose Thinking 

Increased or Decreased Sexuality

May include inappropriate or sexual behavior 

Changes in Thought Patterns

Distractibility


Creative Thinking


Flight of Ideas


Disorientation


Disjointed Thinking


Racing Thoughts 

Changes in Mood

Irritability


Excitability


Hostility


Feelings of Exhilaration 

Changes in Perceptions

Inflated Self-Esteem


Hallucinations (not present in hypomania)


Delusions (not present in hypomania)


Paranoia (generally not severe in hypomania)


Increased Religious Activities 

Hypomania also differs from bipolar mania in that the symptoms are generally less severe so that they do not cause significant impairment of daily activities.

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