On October 3, 1849, Poe was found on the streets of Baltimore, delirious and "in great distress, and... in need of immediate assistance," according to the man who found him. He was taken to the Washington College Hospital, where he died early on the morning of October 7. Poe was never coherent long enough to explain how he came to be in his dire condition, and, oddly, was wearing clothes that were not his own. Poe is said to have repeatedly called out the name "Reynolds" on the night before his death, though no one has ever been able to identify the person to whom he referred. One Poe scholar, W. T. Bandy, has suggested that he may instead have called for "Herring," (Poe's uncle was called Henry Herring). Some sources say Poe's final words were " Lord help my poor soul."
The precise cause of Poe's death is disputed. Dr. J. E. Snodgrass, an acquaintance of Poe who was among those who saw him in his last days, was convinced that Poe died as a result of alcoholism and did a great deal to popularize this interpretation of the events. He was, however, a supporter of the temperance movement who found Poe a useful example in his work; later scholars have shown that his account of Poe's death distorts facts to support his theory. Dr. John Moran, the physician who attended Poe, stated in his own 1885 account that "Edgar Allan Poe did not die under the effect of any intoxicant, nor was the smell of liquor upon his breath or person." This was, however, only one of several sometimes contradictory accounts of Poe's last days he published over the years, so his testimony cannot be considered entirely reliable.
Numerous other theories have been proposed over the years, including several forms of rare brain disease, diabetes, various types of enzyme deficiency, syphilis, the idea that Poe was shanghaied, drugged, and used as a pawn in a ballot-box-stuffing scam during the election that was held on the day he was found, and, more recently, rabies. The rabies death theory was proposed by Dr. R. Michael Benitez, and is based upon the fact that Poe's symptoms before death are similar to those displayed in a classic case of rabies. Cats play a prominent part in many of his stories. It is conjectured that he was accidentally bitten by a rabid pet.
In the absence of contemporary documentation (all surviving accounts are either incomplete or published years after the event; even Poe's death certificate, if one was ever made out, has been lost), it is likely that the cause of Poe's death will never be known.
Poe is buried on the grounds of Westminster Hall and Burying Ground, now part of the University of Maryland School of Law in Baltimore.
Even after death Poe has created controversy and mystery. Because of his fame, school children collected money for a new burial spot closer to the front gate. He was reburied on October 1, 1875. A celebration was held at the dedication of the new tomb on November 17. Likely unknown to the reburial crew, however, the headstones on all the graves, previously facing to the east, were turned to face the West Gate in 1864. Therefore, as it was described in a seemingly fitting turn of events:
In digging on what they erroneously thought to be the right of the General Poe the committee naturally first struck old Mrs. Poe who had been buried thirty-six years before Edgar's mother-in-law; they tried again and presumably struck Mrs. Clemm who had been buried in 1876 only four years earlier. Henry's Poe's brother foot stone, it there, was respected for they obviously skipped over him and settled for the next body, which was on the Mosher lot. Because of the excellent condition of the teeth, he would certainly seem to have been the remains of Philip Mosher Jr, of the Maryland Militia, age 19.